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How aging cells disrupt communication between organs
Updated
Abstract
Essence
The article proposes senescent cells as mediators of aging signals between organs.
Evidence
This opinion article synthesizes recent work on senescence-associated secretory phenotype signaling, immune aging, and inflammaging.
Caveat
Because it is a conceptual synthesis, it does not directly test whether targeting senescent cells mitigates systemic aging through interorgan communication.
Simplified
Longevity & Aging