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Abstract
Cellular senescence is characterized by the arrest of the cell cycle in the G1 phase.
- Cellular senescence, immunosenescence, and inflammaging are natural processes associated with aging.
- Immunosenescence involves chronic inflammation and reduced immune response effectiveness, which could lead to chronic diseases.
- Inflammaging refers to the immune system's dysregulation linked to advanced age.
- Senolytic drugs that eliminate senescent cells and senomorphic drugs that inhibit inflammatory mediators are being explored as potential treatments.
- These therapies may help delay, prevent, or improve age-related diseases.
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