Nature aging

Senolytic treatment in old mice may change immune, scar tissue, and metabolism functions

Updated

Abstract

D+Q treatment may systematically attenuate several aging hallmarks in aged mice.

  • D+Q showed potential to enhance immune cell function and maintain population stability.
  • The treatment alleviated tissue inflammation and improved metabolic profiles.
  • Starting the intervention during early aging and prolonging treatment could lead to better outcomes than late-stage treatment.
  • Findings suggest that the efficacy of D+Q is influenced by tissue and cell type.

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