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Abstract
30-35% of patients with treatment-resistant depression respond to ketamine or esketamine treatment.
- Increased levels of brain-derived neurotrophic factor (BDNF) in the serum may indicate a positive response to antidepressant treatment.
- Previous studies have focused on the effects of single intravenous doses of ketamine.
- The relationship between BDNF expression and various treatment schedules has not been fully established.
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