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Sex differences in response to longevity interventions
How males and females respond differently to treatments that may extend lifespan
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Abstract
Interventions to extend lifespan and healthspan may affect male and female organisms differently.
- Sex-specific differences in baseline lifespan and characteristics such as body size and metabolism may influence responses to lifespan-extending interventions.
- Current literature indicates that males and females respond differently to various interventions aimed at extending lifespan.
- Differences in gonadal hormone levels or chromosome status could play a role in how aging interventions affect males and females.
- Understanding sex as a biological variable in aging may uncover distinct strategies for improving healthspan and addressing age-related diseases.
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