EClinicalMedicine

Stroke risk linked to SGLT2 inhibitors, GLP-1 receptor agonists, and DPP-4 inhibitors in people with type 2 diabetes in Sweden

Updated

Abstract

Meta-analyses indicate a protective effect for GLP-1 receptor agonists on stroke risk in individuals with type 2 diabetes.

  • SGLT2 inhibitors and DPP-4 inhibitors show neutral findings regarding stroke risk.
  • Observational studies suggest potential broader stroke risk reductions associated with these medications.
  • The study utilized nationwide longitudinal data to estimate associations with stroke risk.
  • Results were contextualized within existing meta-analyses of randomized controlled trials and observational studies.

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