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Abstract
Psychedelics exhibit substantial diversity in chemical structure and duration of action, influencing their therapeutic potential.
- Short-acting psychedelics may be advantageous for brief therapeutic sessions.
- Long-acting psychedelics could be more effective for achieving clinical outcomes.
- Differences in receptor binding and metabolism are associated with the varying effects of these compounds.
- Functional group modifications play a critical role in determining receptor binding affinity and efficacy.
- Insights from synthetic chemistry and pharmacology are essential for developing next-generation psychedelic therapies.
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