Bidirectional Communication

Mar 5, 2026The Veterinary clinics of North America. Small animal practice

Two-Way Communication Between the Gut and Brain in Pet Health

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Abstract

The microbiome-gut-brain axis (MGBA) connects gastrointestinal microbial activity with various bodily systems, influencing health.

  • Disruptions in the MGBA can lead to dysbiosis, immune dysregulation, and inflammation.
  • Changes in gut microbial composition and diversity are linked to several disease states and behavioral disorders.
  • Psychoactive treatments may aim to target the MGBA to alleviate neuroinflammation associated with gastrointestinal and neuropsychiatric conditions.

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