Comparative analysis of 5-year efficacy and outcomes of single anastomosis procedures as revisional surgery for weight regain following sleeve gastrectomy

Jul 11, 2023Surgical endoscopy

Five-year results of single connection surgeries to fix weight regain after sleeve gastrectomy

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Abstract

Significant weight loss at 5 years post-procedure was observed, with the SADI-S group losing an average of 30.0% of total body weight compared to 19.4% in the OAGB-MGB group.

  • The SADI-S group showed a greater percentage of total weight loss than the OAGB-MGB group at the 5-year follow-up.
  • Remission of diabetes and hypertension was more common in patients who underwent the SADI-S procedure.
  • The OAGB-MGB group experienced a higher rate of complications compared to the SADI-S group.
  • Reoperations were more frequent in the OAGB-MGB group, with 5 patients requiring reoperation compared to 1 in the SADI-S group.
  • No mortality events occurred in either group during the study period.

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Key numbers

30.0 Β± 18.4
Increase in (TWL%)
TWL% for SADI-S group at 5 years follow-up.
6 of 8
Resolution of Type 2 Diabetes (T2D)
Patients with T2D in SADI-S group achieving remission.
28.6%
Complication Rate
Complication rate in OAGB-MGB group.

Full Text

What this is

  • This research compares the effectiveness of two revisional weight-loss surgeries: Single Anastomosis Duodeno-Ileal Bypass (SADI-S) and One Anastomosis Gastric Bypass (OAGB-MGB).
  • The study focuses on patients who regained weight after Sleeve Gastrectomy (SG) and underwent these procedures with at least 5 years of follow-up.
  • Key outcomes assessed include weight loss, resolution of comorbidities, complications, and reoperation rates.

Essence

  • SADI-S outperforms OAGB-MGB in weight loss and comorbidity resolution after revisional surgery for weight regain post-sleeve gastrectomy. Complication and reoperation rates were also lower in the SADI-S group.

Key takeaways

  • SADI-S led to a (TWL%) of 30.0 Β± 18.4, significantly higher than the 19.4 Β± 16.3 in the OAGB-MGB group. This indicates that SADI-S is more effective for weight loss.
  • Resolution of comorbidities such as diabetes and hypertension was more common in the SADI-S group. For instance, 75% of patients with diabetes in the SADI-S group achieved remission.
  • Complication rates were lower in the SADI-S group (21.42%) compared to OAGB-MGB (28.6%). Fewer patients required reoperations in the SADI-S group, indicating better safety.

Caveats

  • The study's retrospective design may introduce biases, limiting the strength of conclusions. Additionally, quality of life post-surgery was not assessed.
  • The follow-up duration was limited to 5 years, which may not capture long-term outcomes and complications associated with these procedures.

Definitions

  • Total Weight Loss Percentage (TWL%): The percentage of total body weight lost after surgery compared to preoperative weight.
  • Excess Weight Loss Percentage (EWL%): The percentage of excess body weight lost after surgery compared to the ideal body weight.
  • Remission of Comorbidities: The resolution of obesity-related conditions such as diabetes and hypertension, often defined by specific clinical criteria.

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