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Single-cell and spatial detection of senescent cells using DeepScence
Detecting aging cells individually and in their tissue location using DeepScence
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Abstract
DeepScence can accurately identify senescent cells in single-cell and spatial transcriptomics data.
- DeepScence utilizes a deep neural network to pinpoint senescent cells.
- The method is based on a curated set of senescence-associated genes.
- It outperforms existing techniques in identifying senescent cells across multiple data collection platforms.
- Demonstrated effectiveness includes both in vitro and in vivo gene expression data.
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