We can’t show the full text here under this license. Use the link below to read it at the source.
Single-cell and spatial detection of senescent cells using DeepScence
Detecting aging cells one by one and in their tissue location using DeepScence
AI simplified
Abstract
DeepScence can accurately identify senescent cells in single-cell and spatial transcriptomics data.
- DeepScence utilizes a deep neural network approach to enhance the identification of senescent cells.
- The method incorporates a curated gene set, CoreScence, which combines information from multiple published sources.
- DeepScence has shown superior performance compared to existing methods in identifying senescent cells.
- The accuracy of DeepScence was validated using both in vitro and in vivo single-cell gene expression data.
- It also effectively analyzes spatial transcriptomics data from various platforms.
AI simplified