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Common sleep characteristics and the risk of common perinatal complications and adverse outcomes: a multi-sample, bidirectional Mendelian randomization study
Common sleep patterns and their links to common pregnancy problems and outcomes
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Abstract
Sleeplessness is associated with preterm birth, while sleep duration is linked to gestational diabetes.
- Sleep characteristics may be causal risk factors for perinatal complications and adverse outcomes.
- Narcolepsy is associated with pregnancy hypertension and eclampsia.
- The analysis utilized seven common sleep characteristics and twelve perinatal complications.
- Results were consistent across multiple analytical methods, reinforcing the findings.
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Key numbers
1.996
Increased Risk of Preterm Birth
for preterm birth associated with sleeplessness
1.498
Increased Risk of Gestational Diabetes
for gestational diabetes associated with sleep duration
3.335
Higher Risk of Pregnancy Hypertension
for pregnancy hypertension associated with narcolepsy