Sleep disturbances, functioning, and quality of life in euthymic patients with bipolar disorder

Sep 10, 2018Psychiatry research

Sleep problems, daily functioning, and quality of life in stable bipolar disorder patients

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Abstract

Almost half of the 119 euthymic bipolar patients reported at least one sleep complaint.

Nighttime awakenings were reported by 60.5% of patients, while 31.9% experienced difficulty falling asleep.
Long sleep duration was linked to worse global and occupational functioning.
Sleep satisfaction was negatively correlated with quality of life in mental health measures.
The use of benzodiazepines adversely affected quality of life in these patients.
Sleep disturbances may contribute to impaired functioning and quality of life in euthymic bipolar patients.

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There is scarce knowledge about the impact of sleep disturbances on functioning and quality of life (QoL). This study aims to investigate the links between sleep satisfaction and duration, and functioning and QoL in euthymic BD patients. We made a secondary analysis of a cross-sectional, naturalistic, multicenter study. Inclusion criteria: DSM-IV BD diagnosis; age > 17 years; written informed consent. Sample: 119 Spanish euthymic BD outpatients. Hierarchical multiple regressions were performed controlling for confounding factors. We found that almost half of the patients reported at least one sleep complaint, nighttime awakenings (60.5%) and difficulty falling asleep (31.9%) were the most frequent. Long sleep duration was associated with worse global functioning, and also with worse occupational functioning along with caffeine consumption. Sleep satisfaction was negatively associated with worse QoL in the mental health subscale and the summary mental. In both cases, the use of benzodiazepines negatively affects these QoL domains. In conclusion, euthymic bipolar patients frequently present sleep disturbances that seem to contribute to the impairment of their functioning and QoL. Also, the use of benzodiazepines negatively affects the QoL of these patients. Thus, a detailed sleep evaluation should be performed, and the use of benzodiazepines should be reduced to the minimum.

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Sleep disturbances, functioning, and quality of life in euthymic patients with bipolar disorder

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