Sleep and physical activity in relation to all-cause, cardiovascular disease and cancer mortality risk

After an average follow-up of 11.1 years, the no moderate-to-vigorous physical activity and poor sleep group had the highest mortality risks.

• Sleep scores are associated with increased mortality risks for all-cause, total cardiovascular disease (CVD), and ischaemic stroke.
• The no moderate-to-vigorous physical activity and poor sleep group had hazard ratios of 1.57 for all-cause mortality and 1.67 for total CVD mortality compared to the high physical activity and healthy sleep group.
• Poor sleep is linked to elevated risks for total cancer (1.45) and lung cancer (1.91) mortality in individuals with no moderate-to-vigorous physical activity.
• The negative effects of poor sleep on mortality are more pronounced in individuals with lower levels of physical activity.

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