Relationships between sleep traits and lung cancer risk: a prospective cohort study in UK Biobank

An 18% higher lung cancer risk is associated with short sleepers and a 17% higher risk with long sleepers compared to normal sleepers (7-8 hours/day).

• A U-shaped relationship exists between sleep duration and lung cancer risk.
• Evening preference is linked to a 25% increased risk of lung cancer compared to morning preference.
• No significant association was found between insomnia or snoring and lung cancer risk.
• Individuals with unfavorable sleep duration or evening preference and high genetic risk showed the highest lung cancer risk.
• The greatest risk was observed in those with both short (<7 hours) or long (>8 hours) sleep duration and high genetic risk.

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