Fertility and sterilityJul 13, 2014

How changing light colors with filters affects melatonin levels

Circadian Biology Weekly Brief ↗PubMed ↗DOI ↗

Updated Mar 22, 2026

Abstract

Filtering short wavelengths below 480 nm from nocturnal lighting may improve mood, cognitive performance, and sleep quality in shiftworkers.

Shiftwork is associated with various health issues, including cancer, heart disease, metabolic disturbances, depression, and anxiety.
Nighttime light exposure disrupts physiological rhythms by misaligning circadian rhythms with environmental cues.
Using optical filters to block certain wavelengths of light during nighttime can reduce changes in hormone levels and gene expression related to circadian rhythms.
Improvements in mood and cognitive performance were observed in both laboratory and field studies when using optical filters.
Participants experienced increased sleep duration and quality following night shifts when optical filters were utilized.

Simplified

Shiftwork has been identified as a risk factor for various medical problems, such as cancer, heart disease, metabolic disturbances, depression, and anxiety disorders, and as reviewed this month, adverse reproductive function. Shiftwork misaligns physiological rhythms with respect to each other and to external environmental rhythms such as the 24-hour light/dark cycle. Light is the strongest time cue for entraining circadian rhythms in mammals, and aberrant light exposure patterns during shiftwork is one of the key factors that induce circadian misalignment. We have recently demonstrated, in both animal and clinical models, that filtering short wavelengths (below 480 nm) from nocturnal lighting can attenuate alterations in hormone secretion (melatonin and glucocorticoids) and in central and peripheral clock gene expression induced by nighttime light exposure. We also demonstrated that the use of optical filters led to an improvement in mood and in cognitive performance under controlled laboratory conditions and during field-based shiftwork studies. Moreover, there was an increase in sleep duration and quality on nights immediately following night shifts. We believe it is likely that optical filters incorporated into glasses or as coverings for light bulbs could be used as a method to improve or prevent many of the medical problems associated with circadian misalignment and rotating shiftwork.

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How changing light colors with filters affects melatonin levels

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