Frontiers in neuroendocrinology

The brain's internal clock controlling seasonal rhythms

Updated

Abstract

The suprachiasmatic nucleus (SCN) encodes changes in day length to regulate seasonal physiology and behavior.

  • SCN neurons function as independent oscillators, working together to create a unified circadian rhythm.
  • Photic information is received by the SCN, influencing melatonin production in the pineal gland.
  • Adaptations to varying light conditions lead to alterations in neurotransmitter levels and clock gene expression within the SCN.
  • These changes result in variations in rhythmic electrical activity, an important output of the SCN.
  • Efferent pathways from the SCN control the timing of reproductive cycles and hibernation.
  • In humans, the SCN exhibits seasonal changes in neurotransmitter levels and structure.

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