Systemic and Cellular Reflections on Ageing and the Circadian Oscillator – A Mini-Review

Oct 29, 2010Gerontology

How aging affects the body and cells’ internal daily clocks

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Abstract

Therapies aimed at sustaining circadian function may increase quality of life in elderly patients.

  • A circadian clock regulates various physiological processes in mammals in alignment with the solar day.
  • Normal aging is associated with a gradual erosion of this daily physiological coordination.
  • Pathological aging may further exacerbate this erosion of circadian synchronization.
  • Understanding the relationship between the circadian clock and aging at both cellular and systemic levels could provide insights for improving elderly health.

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