Gerontology

How aging affects the body and cells’ internal daily clocks

Circadian Biology Weekly Brief ↗PubMed ↗DOI ↗

Updated

Abstract

Therapies aimed at sustaining circadian function may increase quality of life in elderly patients.

  • A circadian clock regulates various physiological processes in mammals in alignment with the solar day.
  • Normal aging is associated with a gradual erosion of this daily physiological coordination.
  • Pathological aging may further exacerbate this erosion of circadian synchronization.
  • Understanding the relationship between the circadian clock and aging at both cellular and systemic levels could provide insights for improving elderly health.

Simplified

Full Text

Full text is available at the source.
View Full Text ↗

Related papers

Jun '14
How the Body’s Internal Clock May Affect Cancer Treatment
cited by 9 papers
editorial
Jun '14
The body’s internal clock system in cancer treatment
cited by 182 papers
journal article
May '20
Daily body clock effects on drug processing and its importance for timed treatments
cited by 116 papers
research support, non-u.s. gov't
Nov '09
Changing the body’s internal clock to help prevent cancer, control its growth, and ease cancer symptoms
top 30% journal
cited by 61 papers
multicenter study
Sep '10
How Stress Hormones and Body Clocks Together Influence Cell Growth
top 20% journal
cited by 42 papers
journal article

What Lands in Your Inbox Each Week:

  • 📚7 fresh studies
  • 📝plain-language summaries
  • ✅direct links to original studies
  • 🏅top journal indicators
  • 📅weekly delivery
  • 🧘‍♂️always free

Recent issues from the circadian biology brief

issue #49
Your body clock controls which drugs work — and a protein called gp78 is why
6 days ago7 studies
issue #48
A blood test can now estimate your internal clock time using just 60 proteins
1 week ago7 studies
issue #47
Your body clock controls liver fibrosis — and scientists just found the on/off switch
2 weeks ago7 studies
issue #46
Night shift workers' metabolomes fall out of sync — and glucose pays the price
3 weeks ago7 studies
issue #45
80% of FDA-approved drug targets show clock-dependent activity — timing may be everything
4 weeks ago7 studies
issue #44
Sleeping late on weekends is independently linked to higher cardiovascular disease risk
5 weeks ago7 studies
issue #43
A smartphone app cut mood episode recurrence 3.4x in people with depression and bipolar disorder
6 weeks ago7 studies
issue #42
Morning cancer immunotherapy linked to 49% vs 40% disease control rate in 969 patients
7 weeks ago7 studies
issue #41
Timing cancer treatment before 3pm nearly doubled survival in lung cancer patients
8 weeks ago7 studies
issue #40
Male mice lived 12% longer when they ate only during an 8-hour window at night
9 weeks ago7 studies
explore the archive
See more issues from the circadian biology brief