Telmisartan 80 mg/Hydrochlorothiazide 25 mg Provides Clinically Relevant Blood Pressure Reductions Across Baseline Blood Pressures

Telmisartan 80 mg combined with hydrochlorothiazide 25 mg resulted in a mean systolic blood pressure reduction of -39.2 mmHg in patients with baseline systolic blood pressure of 170 mmHg or higher.

• Combination treatment with telmisartan and hydrochlorothiazide was more effective in reducing blood pressure than telmisartan alone.
• In patients with systolic blood pressure ≥170 mmHg, the combination therapy showed a greater reduction compared to both telmisartan monotherapy and placebo.
• Patients with diastolic blood pressure ≥105 mmHg experienced mean reductions of -20.4 mmHg with the combination therapy, compared to -12.2 mmHg with telmisartan alone.
• The combination therapy was particularly effective in black patients with hypertension, regardless of their baseline blood pressure.
• In patients with hypertension and type 2 diabetes or moderate to severe renal impairment, the combination therapy consistently outperformed telmisartan monotherapy.

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