Tirzepatide in Hispanic/Latino Patients With Type 2 Diabetes: A Subgroup Analysis of the SURPASS Program

Aug 21, 2023The Journal of clinical endocrinology and metabolism

Tirzepatide treatment in Hispanic/Latino people with Type 2 diabetes: Results from a subgroup analysis

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Abstract

decreased significantly from baseline by 1.9% to 2.7% in Hispanic/Latino patients and 1.7% to 2.5% in non-Hispanic/Latino patients treated with tirzepatide.

  • Body weight decreased significantly in Hispanic/Latino patients by 5.3 kg to 12.4 kg and in non-Hispanic/Latino patients by 6.5 kg to 17.1 kg.
  • Treatment-emergent adverse events occurred at similar rates in both Hispanic/Latino and non-Hispanic/Latino subgroups, primarily involving gastrointestinal disorders.
  • The incidence of hypoglycemia was low across both ethnic groups.
  • Efficacy and safety trends were consistent between Hispanic/Latino and non-Hispanic/Latino patients within the overall trial populations.

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Key numbers

1.9% to 2.7%
Reduction
Reduction from baseline in Hispanic/Latino patients.
5.3 kg to 12.4 kg
Body Weight Reduction
Change from baseline in Hispanic/Latino patients.
6.5 kg to 17.1 kg
Body Weight Reduction
Change from baseline in non-Hispanic/Latino patients.

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