Transcriptional activation and repression in the plant circadian clock: Revisiting core oscillator feedback loops and output pathways

Jun 12, 2025Plant communications

How Gene Activation and Repression Shape the Plant Biological Clock and Its Feedback and Output Systems

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Abstract

Transcription factors in plant circadian clocks may function as both activators and repressors of gene expression.

  • The plant circadian clock consists of interconnected feedback loops involving transcriptional activators and repressors.
  • Most identified transcription factors in these loops are repressors, suggesting a model dominated by repressive interactions.
  • Recent studies indicate the presence of transcriptional activators in newly identified feedback loops.
  • Some transcription factors may act as both activators and repressors, expanding understanding of clock regulatory mechanisms.
  • The review provides a framework for understanding the roles of transcriptional activation and repression in core oscillator genes.

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