Innere Medizin (Heidelberg, Germany)

Treating Type 2 Diabetes

Updated

Abstract

Pharmacotherapy now prioritizes cardiorenal protection using sodium-glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists.

  • Modern diabetes treatment is shifting from a focus on glucose levels to a risk-adapted approach that considers individual patient needs.
  • Differentiated phenotyping allows for the early identification of organ-specific risks in individuals with diabetes.
  • SGLT2 inhibitors and GLP-1 receptor agonists may reduce cardiovascular events beyond just lowering blood sugar levels.
  • Continuous glucose monitoring (CGM) offers dynamic metrics, such as time in range, that enhance traditional diabetes management.
  • Metabolic remission is becoming a realistic therapeutic goal, especially when interventions occur early during prediabetes.

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