1,2,3-Triazole-containing hybrids as leads in medicinal chemistry: A recent overview

Jul 14, 2019Bioorganic & medicinal chemistry

Recent overview of 1,2,3-triazole-based compounds as promising drug candidates

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Abstract

1,2,3-triazole-containing hybrids and conjugates have been identified as lead compounds for various biological targets.

  • These compounds may exhibit properties such as anticancer, antimicrobial, and antiviral activities.
  • 1,2,3-triazoles can be synthesized using 'click' chemistry methods, which involve copper- or ruthenium-catalysed reactions.
  • Recent advancements in this area have led to the creation of a novel class of compounds.
  • The review covers developments in medicinal chemistry related to these triazole-containing compounds published in 2018.
  • Findings may assist researchers in organic synthesis, medicinal chemistry, phytochemistry, and pharmacology.

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