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Abstract
Essence
Urinary microRNAs may provide a non-invasive clock for estimating biological age.
Evidence
This machine-learning biomarker study used 6331 adults and reported independent-validation accuracy of MAE ≈ 4.4 years and R² ≈ 0.79.
Caveat
The urinary clock was slightly less accurate than DNA-methylation clocks, and the abstract does not show that it predicts clinical outcomes.
Simplified
Longevity & Aging