Vortioxetine for the treatment of major depressive disorder

Aug 29, 2014Expert review of clinical pharmacology

Vortioxetine as a treatment for major depression

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Abstract

Vortioxetine is an efficacious antidepressant that targets multiple serotonin receptors and the serotonin transporter.

  • Vortioxetine produces antidepressant and anxiety-reducing effects.
  • Administration of vortioxetine may enhance cognitive performance in rodents.
  • Clinical trials indicate vortioxetine is effective and well-tolerated in patients with depression.
  • The drug has a specific positive impact on cognitive symptoms in depressed patients.
  • Vortioxetine offers a unique mechanism of action, presenting a new therapeutic option.

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