EClinicalMedicine

Weight loss and blood pressure changes with GLP-1 and multi-hormone drugs in overweight and obese adults

Updated

Abstract

Weight reduction is recommended for blood pressure management in adults with obesity.

  • Obesity and hypertension often occur together.
  • Glucagon-like peptide-1 receptor agonists (GLP-1RAs) and multi-hormone receptor modulators (MHRMs) are linked to significant weight loss.
  • Modest blood pressure reductions are observed with GLP-1RAs and MHRMs.
  • The relationship between weight loss and blood pressure lowering across these therapies is not fully understood.

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