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Adult mesenchymal stem cells and their exosomes: Sources, characteristics, and application in regenerative medicine
Adult mesenchymal stem cells and their tiny particles: origins, features, and use in healing damaged tissues
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Abstract
Human mesenchymal stem cells (MSCs) are genomic stable and possess self-renewal abilities.
- MSCs can be sourced from bone marrow, adipose tissues, umbilical cord, and placental tissues.
- They can be cultured through multiple undifferentiated passages to develop into specialized cells.
- MSCs produce secretory factors and support trophic functions in the body.
- Exosomes derived from MSCs may have therapeutic potential similar to that of the parent cells.
- The combination of MSCs and their exosomes with biomaterials could enhance tissue and organ regeneration.
- Challenges remain regarding the characteristics of MSCs-exosomes and the barriers to their clinical application.
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