Full text is available at the source.
Aging changes daily biological rhythms in the mouse eye
Updated
Abstract
The retina shows the most significant aging-related changes in circadian rhythm among ocular tissues.
- The eye has its own circadian system that functions separately from the brain's master clock.
- Disruption of the ocular circadian clock may harm overall eye health.
- Aging negatively impacts the circadian rhythm of the retina more than that of the retinal pigment epithelium and cornea.
- Reduction in the amplitude of circadian rhythms is likely a major effect of aging on the circadian clock in various tissues.
Simplified