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Aging Alters Circadian Rhythms in the Mouse Eye
Aging changes daily biological rhythms in the mouse eye
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Abstract
The retina shows the most significant aging-related changes in circadian rhythm among ocular tissues.
- The eye has its own circadian system that functions separately from the brain's master clock.
- Disruption of the ocular circadian clock may harm overall eye health.
- Aging negatively impacts the circadian rhythm of the retina more than that of the retinal pigment epithelium and cornea.
- Reduction in the amplitude of circadian rhythms is likely a major effect of aging on the circadian clock in various tissues.
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