Using AI to find a mouse model of Alzheimer's disease without symptoms

Declarations. Ethics approval and consent to participate: Not applicable. Since we used postmortem brain tissue, consent was not necessary. Consent for publication: Not applicable. Competing interests: D.S is a co-founder of the company RNACheck. S.K.M. is the founder of CgA Therapeuticals, Inc. and co-founder of Siraj Therapeutics. The remaining authors declare no competing interests. A U.S. patent (No. PCT/US2025/053203) was filed on October 29, 2025, listing Sushil K. Mahata, and Suborno Jati as co-inventors. A new disclosure with Case Number SD2025-405 was submitted to UCSD on June 9, 2025.