Alcohol consumption and risk of inflammatory bowel disease among three prospective US cohorts

Dec 9, 2021Alimentary pharmacology & therapeutics

Alcohol drinking and the risk of inflammatory bowel disease in three US groups followed over time

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Abstract

Across 5,170,474 person-years of follow-up, 370 cases of Crohn's Disease and 486 cases of Ulcerative Colitis were documented.

  • No overall association was found between alcohol consumption and the risk of Crohn's Disease or Ulcerative Colitis.
  • For those consuming 15.0+ grams of alcohol per day, the adjusted hazard ratios were 0.84 for Crohn's Disease and 1.08 for Ulcerative Colitis compared to non-users.
  • Moderate consumption of beer (more than 1-4 servings per week) may be associated with a reduced risk of Crohn's Disease.
  • Consumption of more than 4 servings per week of liquor could be linked to an increased risk of Ulcerative Colitis.
  • Further investigation is needed to explore the associations between specific types of alcohol and the risk of these diseases.

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