Associations between ambient fine particulate (PM2.5) exposure and cardiovascular disease: findings from the China Health and Retirement Longitudinal Study (CHARLS)

Sep 27, 2021Environmental science and pollution research international

Links between air pollution (PM2.5) and heart disease in middle-aged and older adults in China

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Abstract

An adjusted odds ratio of 1.18 indicates that for each 10 μg/m³ increase in ambient fine particulate matter, the prevalence of cardiovascular disease is associated with increased risk.

Long-term exposure to fine particulate matter (PM) is linked to cardiovascular disease (CVD) among middle-aged and older adults.
The analysis involved 13,484 adults aged 45 and older surveyed in China.
Stratified analyses suggest that the elderly may be particularly vulnerable to the effects of PM on CVD.
Approximately 20.27% of CVD cases may be attributable to PM exposure.
The findings reinforce the potential health risks associated with long-term PM exposure in developing countries.

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The evidence regarding the association between long-term fine particulate (PM) exposure and cardiovascular disease (CVD) in developing countries is limited. This study investigated the association between long-term exposure to PMand the prevalence of CVD among middle-aged and older adults. A total of 13,484 adults ≥ 45 years of age were surveyed in China, and logistic regression models were used to examine the association between PMand the prevalence of CVD. Furthermore, stratified analyses were conducted to explore potential effect modifiers. In addition, the burden of CVD attributable to PMwas estimated. The analyses revealed that PMwas associated with CVD, with an adjusted odds ratio (OR) of 1.18 (95% confidence interval [CI]: 1.12, 1.26) for each 10 μg/mincrement in ambient PM. Stratified analyses found that the elderly may be a vulnerable population. It was further estimated that approximately 20.27% (95% CI: 11.86%, 29.96%) of CVD cases could be attributable to PM. This nationwide study confirmed that long-term exposure to PMwas associated with an increased prevalence of CVD in China. 2.5 2.5 2.5 2.5 2.5 2.5 2.5 2.5 3

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Associations between ambient fine particulate (PM2.5) exposure and cardiovascular disease: findings from the China Health and Retirement Longitudinal Study (CHARLS)

Abstract

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