Full text is available at the source.
Anti‐obesity and hypolipidaemic effects of Nelumbo nucifera seed ethanol extract in human pre‐adipocytes and rats fed a high‐fat diet
Nelumbo nucifera seed extract reduces fat cell growth and blood fat levels in human cells and high-fat diet rats
AI simplified
Abstract
In vivo administration of Nelumbo nucifera seed ethanol extract (NSEE) resulted in significantly reduced body weight gain and adipose tissue weights in rats.
- In vitro, NSEE inhibited lipid accumulation and reduced the expression of key genes involved in fat cell differentiation.
- Cultured human pre-adipocytes treated with NSEE showed decreased levels of glucose transporter 4 (GLUT4) and leptin.
- Rats on a high-fat diet showed lower serum triglyceride and leptin levels when administered NSEE compared to those on the high-fat diet alone.
- NSEE may have beneficial effects on blood lipid profiles and adipose tissue in the context of obesity.
AI simplified