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Children and adolescents with attention deficit hyperactivity disorder and autism spectrum disorder share distinct microbiota compositions
Children and teens with ADHD and autism have unique gut bacteria patterns in common
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Abstract
compositions in children with ADHD and ASD are highly similar and differ from non-related controls.
- Children and adolescents with ADHD and ASD show altered gut microbiota compared to non-affected children.
- Both alpha- and beta-diversity metrics of gut microbiota are similar in ADHD and ASD cases.
- A subset of ADHD and ASD cases has increased levels of (LBP).
- Increased LBP levels are positively correlated with interleukin (IL)-8, 12, and 13 concentrations.
- These findings suggest a possible disruption of the intestinal barrier and immune dysregulation in affected children.
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Key numbers
1.26
Increased Concentration
Effect size comparing ASD cases to ADHD cases
95
Samples Available
Total number of study participants across all groups