A comparative study on dietary diversity and gut microbial diversity in children with autism spectrum disorder, attention‐deficit hyperactivity disorder, their neurotypical siblings, and non‐related neurotypical volunteers: a cross‐sectional study

Apr 2, 2024Journal of child psychology and psychiatry, and allied disciplines

Differences in Diet and Gut Bacteria in Children with Autism, ADHD, Their Typical Siblings, and Unrelated Typical Children

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Abstract

Ninety-eight subjects were included in the study, revealing significant differences in gut microbial diversity between children with autism spectrum disorder (ASD) and non-related neurotypical controls.

  • Children with ASD showed lower gut microbial diversity compared to non-related neurotypical controls.
  • Statistical analysis indicated significant differences in alpha-diversity indices among the groups.
  • No significant differences in dietary diversity were observed across the groups.
  • The findings suggest distinct microbiome profiles associated with ASD, which may be influenced by co-occurring ADHD.
  • Controlling for dietary factors and other confounders is essential for future research on gut microbiota in neurodevelopmental disorders.

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