Gut microbiota profiles of autism spectrum disorder and attention deficit/hyperactivity disorder: A systematic literature review.

Apr 25, 2020Gut microbes

Gut bacteria patterns in autism and ADHD: A systematic review

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Abstract

Twenty-four articles were identified, including 20 studies on autism spectrum disorder (ASD) and 4 on attention-deficit hyperactivity disorder (ADHD).

  • For ASD, several studies indicated a difference in gut microbiota diversity, although no consistent specific bacterial changes were reported across all studies.
  • Common functional characteristics of gut microbiota were identified in individuals with ASD when compared to controls.
  • The results for ADHD were more varied, with no definitive differences in gut microbiota composition observed.
  • The association between gut microbiota and ADHD remains unclear due to the heterogeneous results across studies.
  • Methodological differences among studies hindered the ability to compare findings effectively for both ASD and ADHD.

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Key numbers

20
Total Studies on ASD
Studies investigating gut microbiota in ASD cases.
4
Total Studies on ADHD
Studies investigating gut microbiota in ADHD cases.
733
ASD Cases Included
Total ASD cases included across studies.

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