The use of Atypical antipsychotics in French psychiatric hospitals

Jul 20, 2007Pharmacy world & science : PWS

Use of Unusual Antipsychotic Drugs in French Psychiatric Hospitals

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Abstract

Of 1475 adult inpatients' prescriptions with an antipsychotic drug, 647 involved atypical antipsychotics (AAP), with risperidone and olanzapine making up about 70% of these cases.

  • Atypical antipsychotic prescriptions were primarily for psychotic patients, accounting for 65% of cases.
  • Patients prescribed AAPs for psychosis were generally younger and more likely to be male than those treated for other conditions.
  • Those receiving AAPs for psychosis were also prescribed higher daily doses and more often received additional neuroleptic and anticholinergic medications.
  • Only 9.1% of AAP prescriptions were for bipolar disorders, with clozapine not being utilized for this indication.
  • In bipolar disorder cases, AAPs were often prescribed alongside mood stabilizers rather than as replacements.

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