Use of Antipsychotic Medicines in Older Adults

Consensus was reached on 78% of treatment options rated by experts for antipsychotic use in older patients.

• Antipsychotics were not recommended for panic disorder, generalized anxiety disorder, and several other conditions without major psychiatric syndromes.
• For agitated dementia with delusions, the first-line recommendation is an antipsychotic alone, with risperidone favored as the primary choice.
• In late-life schizophrenia, risperidone is recommended as the first-line treatment, with other antipsychotics as second-line options.
• The treatment of choice for geriatric psychotic major depression is an antipsychotic combined with an antidepressant.
• Experts advised avoiding certain antipsychotics in patients with diabetes or cardiovascular issues, preferring alternatives like quetiapine for Parkinson's disease.

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