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An anxious relationship between Autism Spectrum Disorder and Gut Microbiota: A tangled chemistry?
Complex links between autism and gut bacteria chemistry
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Abstract
Studies have confirmed a difference in the constitution of gut bacteria among ASD cases and their controls.
- Autism spectrum disorder (ASD) is associated with gastrointestinal issues and immune dysregulation.
- Dysbiosis in the gut microbiota may contribute to the primary stages of ASD.
- A bidirectional connection exists between gut bacteria and the central nervous system, known as the microbiota-gut-brain axis.
- Alterations in gut microbiota have been linked to changes in behavior and metabolic profiles in animal models of ASD.
- Dysregulation in the gut microenvironment may lead to oxidative stress affecting neuronal cells and neurotransmitters.
- Therapy targeting the microbiome could be considered as a potential strategy for addressing ASD symptoms.
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