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Abstract
Organoids may improve regenerative medicine but currently face limitations such as lack of internal vasculature and small size.
- Organoids are three-dimensional structures that mimic specific organs.
- Current organoid technology has advanced but still lacks essential features for effective regenerative medicine.
- Limitations include inadequate internal blood vessel systems, restricted functionality, and small size compared to real organs.
- Reliance on mouse tumor-derived materials for organoid culture raises safety concerns for clinical use.
- Engineering strategies and alternative biocompatible materials could enhance the applicability of organoids in medicine.
- Progress in organoid transplantation shows potential for restoring function in various organs.
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