Understanding the significance of biological clock and its impact on cancer incidence

Dec 15, 2021Cancer letters

How the Body's Internal Clock May Affect Cancer Risk

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Abstract

Circadian disruptions are associated with various diseases, including cancer.

  • Perturbations in circadian rhythms may affect energy balance and lead to changes in the cell cycle.
  • Disruption of the circadian clock is linked to dysregulation of chromatin remodeling.
  • A mechanistic understanding of how circadian disruption enhances cancer risk remains limited.
  • The review discusses the role of the circadian clock in tumor development and the mechanisms involved.
  • Advances in chronotherapy for cancer treatment are highlighted.

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