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Training the Circadian Clock, Clocking the Drugs, and Drugging the Clock to Prevent, Manage, and Treat Chronic Diseases
Using the Body’s Internal Clock and Timing of Medicines to Prevent and Treat Chronic Diseases
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Abstract
Nearly the entire primate genome shows daily rhythms in expression.
- Daily rhythms in behavior, physiology, and metabolism are essential for maintaining body balance.
- Circadian clocks interact with light-dark cycles, sleep-activity cycles, and eating-fasting cycles.
- Disruption of these rhythms, particularly due to light at night, may lead to chronic health risks.
- Molecular rhythms influence key cellular and tissue functions, potentially impacting public health and disease outcomes.
- Recent advancements suggest that enhancing circadian clocks through specific strategies could offer new therapeutic options for diseases like metabolic syndrome and cancer.
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