Trends in pharmacological sciences

Using the Body’s Internal Clock and Timing of Medicines to Prevent and Treat Chronic Diseases

Updated

Abstract

Nearly the entire primate genome shows daily rhythms in expression.

  • Daily rhythms in behavior, physiology, and metabolism are essential for maintaining body balance.
  • Circadian clocks interact with light-dark cycles, sleep-activity cycles, and eating-fasting cycles.
  • Disruption of these rhythms, particularly due to light at night, may lead to chronic health risks.
  • Molecular rhythms influence key cellular and tissue functions, potentially impacting public health and disease outcomes.
  • Recent advancements suggest that enhancing circadian clocks through specific strategies could offer new therapeutic options for diseases like metabolic syndrome and cancer.

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Full Text

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Funding

Competing interests

Conflict of interest : S.P. is the author of the book titled “The Circadian Code” for which he receives author’s royalties. The grant funders nor the publisher of the book had any influence on the content of this article
PubMed

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