The Cochrane database of systematic reviews

Blood pressure lowering effects of combined GIP and GLP-1 receptor activators compared to GLP-1 activators alone

Updated

Abstract

This protocol outlines a Cochrane Review comparing the blood pressure effects of dual GIP/GLP-1 receptor agonists and GLP-1 receptor agonists.

  • The review aims to evaluate differences in blood pressure outcomes between two types of receptor agonists.
  • Dual GIP/GLP-1 receptor agonists may have distinct effects on blood pressure compared to GLP-1 receptor agonists.
  • Understanding these effects could inform treatment strategies for managing blood pressure.

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Funding

Competing interests

GG has received a grant from the French association for balneotherapy research "Association Française pour la Recherche Thermale" (AFRETh, http://www.afreth.org/) that is not related to this review. AG is a PhD candidate funded by RCTs (https://www.rcts.fr/en, an international full‐service clinical research organization) under the "dispositif des Conventions industrielles de formation par la recherche (Cifre)" French policy and his PhD funding is not related to this review. DMS: no relevant interests; Information Specialist of Cochrane Hypertension but was not involved in any part of the editorial process of this review. CDJ: no relevant interests; Managing Editor of Cochrane Hypertension but was not involved in any part of the editorial process of this review. JMW: no relevant interests; Co‐ordinating Editor of Cochrane Hypertension but was not involved in any part of the editorial process of this review. We will follow the Cochrane's Conflict of Interest documentation (COI policy: https://training.cochrane.org/online-learning/coi-policy/coi-policy-cochrane-library), "Anyone engaged in writing a Cochrane review, who has had direct involvement in the conduct, analysis, and publication of a study that could be included in the review, cannot make study eligibility decisions about, extract data from, carry out the risk of bias assessment for, or perform GRADE assessments of that study." None of the authors of this protocol has been involved in any studies expected to be included.
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