Experimental physiologyDec 24, 2013

What Your Body Clock Means for Your Health and Daily Life

Circadian Biology Weekly Brief ↗PubMed ↗DOI ↗

Updated Apr 6, 2026

Abstract

Impairment in mathematical calculations between 04:00 and 06:00 h is worse than that caused by several shots of whisky.

Biological clocks influence sleep patterns, alertness, mood, physical strength, and blood pressure.
Disruption of sleep and circadian rhythms (SCRD) is linked to various health issues, including neuropsychiatric disorders and eye conditions.
SCRD is prevalent among different groups, such as teenagers and shift workers.
The effects of SCRD extend beyond excessive sleepiness, potentially leading to abnormal metabolism, heart disease, reduced immunity, and cognitive and mood disturbances.
Understanding the regulation of 24-hour rhythms may provide insights into improving human health.

Simplified

Until we turned our nights into days and began to travel in aircraft across multiple time zones, we were largely unaware that we possess a 'day within' driven by an internal body clock. Yet the striking impairment of our abilities in the early hours of the morning soon reminds us that we are slaves to our biology. Our ability to perform mathematical calculations or other intellectual tasks between 04.00 and 06.00 h is worse than if we had consumed several shots of whisky and would be classified as legally drunk. Biological clocks drive or alter our sleep patterns, alertness, mood, physical strength, blood pressure and every other aspect of our physiology and behaviour. Our emerging understanding of how these 24 h rhythms are generated and regulated is not only one of the great success stories of modern biology, but is also informing many areas of human health. Sleep and circadian rhythm disruption (SCRD) is a feature shared by some of the most challenging diseases of our time, including neuropsychiatric illness and serious disorders of the eye. Sleep and circadian rhythm disruption is also commonly seen across many sectors of society, from teenagers to shift workers. We also now appreciate that SCRD is far more than feeling sleepy at an inappropriate time. It promotes multiple illnesses ranging across abnormal metabolism, heart disease, reduced immunity, increased stress and abnormal cognition and mood states. This short review considers how 24 h rhythms are generated and regulated, the consequences of working against our body clock and the emerging relationship between SCRD and mental illness.

Full Text

Full text is available at the source.

View Full Text ↗

What Your Body Clock Means for Your Health and Daily Life

Abstract

Full Text

You found one interesting study. We’ll send the next 7.

what lands in your inbox each week:

Recent issues from the circadian biology brief

Abstract

Full Text

Related papers

You found one interesting study. We’ll send the next 7.

what lands in your inbox each week:

Recent issues from the circadian biology brief