Circadian Disruption: comparing humans with mice

Jul 20, 2013Chronobiology international

Comparing Body Clock Disruption in Humans and Mice

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Circadian BiologyCircadian Biology on OpenScience ↗PubMed ↗DOI ↗

Abstract

Phasor magnitudes, a measure of circadian entrainment, were shown to be similar for humans and for mice exposed to similar light-dark patterns.

  • Disruption of the 24-hour light-dark cycle is linked to increased health risks in animals.
  • Comparisons were made between circadian disruption in day-shift and rotating-shift nurses and new mouse data.
  • Circadian disruption may affect both humans and mice in similar ways when exposed to shiftwork-like light patterns.
  • Phasor analyses could potentially connect ecological measurements of circadian disruption in humans with health outcome studies in mice.

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