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Body weight at early and middle adulthood, weight gain and persistent overweight from early adulthood are predictors of the risk of total knee and hip replacement for osteoarthritis
Body weight and weight gain in early and middle adulthood predict the risk of knee and hip replacement for osteoarthritis
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Abstract
Greater weight and BMI at age 18-21 years is associated with a 1.25-fold increased risk of total knee replacement.
- Increased weight and body mass index (BMI) during early and middle adulthood may elevate the risk of knee and hip replacements due to osteoarthritis.
- Weight gain and persistent overweight from early to middle adulthood are linked to a higher risk of total knee and hip replacement.
- The risk associated with middle age weight and BMI is stronger for knee replacement compared to hip replacement.
- For every 5 kg increase in middle age weight, the risk for knee replacement increases by 1.25 times, while the increase for hip replacement is 1.11 times.
- Adult weight gain also significantly elevates the risk for knee replacement more than for hip replacement.
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