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Relationship of weight and obesity with the risk of knee and hip arthroplasty for osteoarthritis across different levels of physical performance: a prospective cohort study
How Body Weight and Obesity Affect the Risk of Knee and Hip Replacement for Osteoarthritis at Different Physical Fitness Levels
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Abstract
Over 9.1 years of follow-up, 317 participants underwent knee and 202 underwent hip arthroplasty for osteoarthritis.
- Participants with both obesity and significantly impaired physical performance had a significantly higher risk of knee arthroplasty (hazard ratio = 5.25) compared to those with neither condition.
- Obesity alone was associated with a hazard ratio of 2.49 for knee arthroplasty, while impaired physical performance alone had a hazard ratio of 2.19.
- For hip arthroplasty, the risk was also greater in those with both obesity and impaired physical performance (hazard ratio = 2.67) compared to obesity alone (1.65) or impaired performance alone (1.83).
- In overweight/obese participants, an increase of 5 kg in baseline weight raised the risk of knee arthroplasty regardless of physical performance level.
- In those with good physical performance, increased weight also heightened the risk of hip arthroplasty.
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