Annals of the rheumatic diseases

Rates of severe knee and hip arthritis linked to different body weight measures in a large population study

GLP-1 Therapies Weekly Brief ↗PubMed ↗DOI ↗

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Abstract

A total of 471 individuals experienced knee osteoarthritis and 551 had hip osteoarthritis over an 11-year period.

  • Higher body mass index (BMI) is associated with an increased risk of knee osteoarthritis, with a relative risk of 8.1 for the highest quartile compared to the lowest.
  • Waist circumference and weight also show significant associations with knee osteoarthritis, with relative risks of 6.7 and 6.5, respectively, for the highest quartile.
  • Body fat percentage (BF%) and waist-hip ratio (WHR) have lower relative risks for knee osteoarthritis at 3.6 and 2.2, respectively.
  • For hip osteoarthritis, the relative risk associated with BMI is 2.6, while weight and waist circumference show relative risks of 3.0 and 2.5, respectively.
  • The findings suggest that measures of overweight may influence the incidence of both knee and hip osteoarthritis.

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