Neuron

Breast cancer disrupts brain circuits that control daily hormone rhythms to help tumors grow

Updated

Abstract

Essence

A highlighted Neuron study suggests breast cancer can blunt daily glucocorticoid rhythms through hypothalamic circuits, and timed neuromodulation may slow tumor growth.

Evidence

This commentary summarizes a study linking breast cancer, hypothalamic CRH neuron disinhibition, glucocorticoid rhythm disruption, CD8 T cell function, and tumor growth attenuation after time-specific neuromodulation.

Caveat

As a commentary, the abstract gives no independent methods, sample size, or human clinical outcome data for chronotherapy.

Simplified

Full Text

Full text is available at the source.

Funding

Competing interests

0 of 2
authors report competing interests
2 report none
PubMed

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