Obesity reviews : an official journal of the International Association for the Study of ObesityJul 22, 2026

Heart health effects of GLP-1 medicines in people with overweight and obesity: A review of clinical trial summaries

GLP-1 Therapies Weekly Brief ↗PubMed ↗DOI ↗OA ↗

Updated Jul 23, 2026

Abstract

A meta-analysis of randomized controlled trials found cardiovascular outcomes of GLP-1-based medicines in the overweight and obese population.

Existing meta-analyses have explored cardiovascular outcomes associated with GLP-1-based treatments.
The focus has been on individuals with overweight and obesity.
A comprehensive summary of these findings is currently absent.

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