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Abstract
Cellular senescence is identified as a key risk factor in chronic inflammatory skin disorders.
- Chronic inflammatory skin disorders involve persistent inflammation and impaired skin barrier function.
- Traditional views attribute disease progression primarily to immune dysregulation.
- Emerging evidence suggests that cellular senescence plays a significant role in these disorders.
- Cellular senescence is characterized by irreversible cell cycle arrest and associated with specific changes in cell function.
- The review discusses the potential for new therapeutic strategies aimed at targeting senescent cells.
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